Sheep Polyclonal IgG Anti-IgG4, human

Basic information

  • Name

    Sheep Polyclonal IgG Anti-IgG4, human

  • Price

    471 EUR

  • Size

    1 ml

  • Catalog number

    IGG4001

More detailed information

Availability

Please contact us to check the availability

Immunogen

Purified human IgG4

Specificity

human IgG4

Species reactivity

Human

Product presentation

Affinity purified antibody in GBS, pH7.4, 0,099% NaN3, 0,1% EACA, 1 mM EDTA, 0,01% Benzamidine

Product category

Primary Antibody

Antibody's raised in

Sheep

Antibody's isotype

IgG

Antibody's clone

polyclonal

Product is supplied as

liquid concentrate

Recommended concentration for use

1:20

Protein concentration

0,1 mg/ml

Tested applications

IEP, WB, ELISA, Immunohistochemistry

Storage method

Store at 2-8°C

Litterature

1. Kleger A, Seufferlein T, Wagner M, Tannapfel A, Hoffmann TK, Mayerle J (2015) IgG4-associated autoimmune diseases—polymorphous presentation complicates diagnosis and treatment. Dtsch Arztebl Int; 112: 128–35. 2. Stone et al. (2012). Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations. Arthritis & Rheumatism. 64 (10): 3061–3067. 3. Deshpande et al. (2012). Consensus statement on the pathology of IgG4-related disease. Modern Pathology. 25 (9): 1181–1192. 4. A. Fernandez-Flores (2012) The role of IgG4 in cutaneous pathology. Rom J Morphol Embryol, 53(2):221-231.

Tips

*Gentaur's antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

About

Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Additional isotype

IgG

Group

Polyclonals and antibodies